Total Repair DNA Serum
Description
Total Repair DNA Serum is the most comprehensive and advanced formula ever at Aesthetics Rx®. With sophisticated recover, repair, and rejuvenating skin benefits this serum is our highest performing, restorative night treatment that healthy, glowing skin cannot do without. 360° anti-ageing skin benefits include:
- Reduction in the signs of accelerated skin ageing
- Smoother, more refined, and supple skin texture
- A more even skin tone
- Powerful defence against pollution and free radical damage
- Improves the appearance of fine lines and wrinkles associated with accelerated skin ageing
- A more radiant and glowing complexion upon waking
We love it because
This lightweight serum-cream fully absorbs on application at night and the skin is noticeably smoother and more radiant the following morning. Containing Retinal, it has the super-power of Vitamin A, but without the unwanted side effects. Peptides and growth factors in this formulation provide unrivalled skin repair and regenerative benefits.
This product is potent. It is designed only for skin that has been prepped in advance. Certain other products mustn’t be used at the same time. Please see usage page.
Upgraded ingredient
We have upgraded the type of retinal we use in Total Repair DNA Serum to a new biotechnology-derived retinal encapsulated within a deep delivery system.
This new encapsulated form protects the active against degradation, maximises delivery to deeper skin levels, and releases gradually for a longer-lasting effect.
In a clinically controlled in vivo study, 30 female volunteers aged 35 to 60 used a gel formulated with 5% of this material over 56 days. Results demonstrated up to +67% improvement in skin firmness, +69% improvement in elasticity, and an 18% reduction in wrinkles, with 100% of volunteers showing measurable firmness improvement. Zero adverse effects were recorded across the entire study cohort.
This upgrade delivers measurably superior anti-ageing outcomes while maintaining an excellent tolerability and safety profile for our customers. Please note that this Vegan Pure Retinal has an orange appearance, which is expected and reflects the nature of this encapsulated ingredient. This is a colour difference from the retinal used previously in the formula and is entirely normal.
Our Packaging
New look, same skin-loving science.
We are transitioning through a complete packaging transformation, and as we move into this new chapter for Aesthetics Rx®, you’ll notice our new designs over the coming 6 months. This re-design is a positive step, especially for the environment; you can learn more here. Meaningful change takes time, especially when done with care, and because this is a phase-in product by product, your order may include a combination of our current and /or new packaging designs.
Rest assured, the product inside remains the exact same high-quality formulation you already know and trust; it is just the packaging that has changed. If your package arrives containing our original design, it means you're helping move through our current products, but if you spot our new look, you're among the first to see it, and we’d love your feedback.

How to
Ingredients
Key Benefits
Free shipping AU wide on orders over $70; express over $150.
Free samples with every order.
Goes well with:
Microbiome Balancing Mist
100ml
$69.00
Out of stockFAQ's
How do I use the new serum dropper?
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Customer Care
Free shipping
Free standard shipping Australia wide over $70; express over $150.
Orders placed Monday to Thursday will be processed the next working day. Orders placed after 11am on Friday will be processed the following Monday.
Order tracking
Once your order has been dispatched, you will receive your tracking number.
Get in touch
The Aesthetics Rx® Customer Care Team is ready to assist you.
Send us an email at customercare@aestheticsskincare.com.au
We're here Monday to Friday 9am – 5pm AEST. Closed public holidays.
Introducing
BIOTECHNOLOGY IN SKINCARE
As consumer interest grows in evidence based, efficacious ingredients, Aesthetics Rx® incorporates biotechnology to develop products with clinically proven actives, that are thoughtfully formulated.
Biotechnology refers to the use of biological systems or components—such as enzymes or plant-derived materials—to create or enhance products for human use. In skincare, this might include using enzymes to gently exfoliate or plant stem cells to support product performance.
Biotech ingredients are developed in laboratories by scientists using plant-based materials and other naturally sourced substances. These processes allow for the creation of ingredients that replicate or improve upon traditional raw extracts. By producing ingredients in controlled environments, biotechnology can help reduce reliance on agricultural resources such as land and water.
